diff --git a/texmf/tex/latex/elife-doi-fix/elife-doi-fix.cls b/texmf/tex/latex/elife-doi-fix/elife-doi-fix.cls
new file mode 100755
index 0000000..3db0766
--- /dev/null
+++ b/texmf/tex/latex/elife-doi-fix/elife-doi-fix.cls
@@ -0,0 +1,527 @@
+% A template for eLife submissions.
+%
+% Created by Overleaf (writeLaTeX).
+%
+\NeedsTeXFormat{LaTeX2e}
+\ProvidesClass{elife}[2022/06/01, v1.11]
+
+%% Move all option processing before loading class
+\newif\if@reqslineno
+\DeclareOption{lineno}{\@reqslinenotrue}
+
+%% Linespacing.
+\newif\if@onehalfspacing
+\newif\if@doublespacing
+\DeclareOption{onehalfspacing}{\@onehalfspacingtrue}
+\DeclareOption{doublespacing}{\@doublespacingtrue}
+
+\DeclareOption*{\PassOptionsToClass{\CurrentOption}{extarticle}}
+\ExecuteOptions{}
+\ProcessOptions\relax
+\LoadClass{extarticle}
+
+\RequirePackage[english]{babel}
+
+\RequirePackage{calc}
+\RequirePackage{etoolbox}
+\RequirePackage{regexpatch}
+\RequirePackage{ifxetex,ifluatex}
+
+\newif\ifxetexorluatex
+\ifxetex
+  \xetexorluatextrue
+\else
+  \ifluatex
+    \xetexorluatextrue
+  \else
+    \xetexorluatexfalse
+  \fi
+\fi
+
+\RequirePackage{amsmath}
+\RequirePackage{mdframed}
+
+\RequirePackage{lineno}
+\if@reqslineno\linenumbers\fi
+
+% Note v1.0 of elife.cls used Trueno font; this was 
+% changed to use Open Sans in v1.1
+\ifxetexorluatex
+  \RequirePackage{unicode-math}
+  % v1.7: xits-math font name changed to XITSMath in TL2019
+  \RequirePackage[default]{opensans}
+  \setmonofont[Scale=MatchUppercase]{Latin Modern Mono}
+  % XITSMath is really STIX. Really.
+  % https://tex.stackexchange.com/questions/227216/stix-versus-xits
+  \setmathfont[Extension = .otf,BoldFont = XITSMath-Bold,]{XITSMath-Regular}
+\else  
+  \RequirePackage[T1]{fontenc}
+  \RequirePackage[utf8]{inputenc}
+  \RequirePackage{stix}
+  \RequirePackage[default]{opensans}
+  \renewcommand{\ttdefault}{lmtt}
+\fi
+
+\RequirePackage{microtype}
+
+% Trueno/Open Sans requires a bigger "single" linespread.
+\linespread{1.2}
+\if@onehalfspacing\linespread{1.5}\fi
+\if@doublespacing\linespread{2.0}\fi
+
+\RequirePackage{graphicx,xcolor}
+\definecolor{eLifeDarkBlue}{HTML}{273B81}
+\definecolor{eLifeLightBlue}{HTML}{0A9DD9}
+\definecolor{eLifeMediumGrey}{HTML}{6D6E70}
+\definecolor{eLifeLightGrey}{HTML}{929497}
+
+\RequirePackage{booktabs}
+\RequirePackage{authblk}
+
+\RequirePackage[left=6cm,%
+                marginparwidth=4cm,%
+                marginparsep=0.5cm,%
+                right=1.3cm,%
+                top=2cm,%
+                bottom=2.5cm,%
+                headheight=21pt,%
+                headsep=2\baselineskip,%
+                columnsep=2em,%
+                letterpaper]{geometry}%
+\RequirePackage{changepage}
+
+\RequirePackage{silence}
+\WarningFilter{caption}{The option `hypcap=true' will be ignored}
+
+\RequirePackage[labelfont={bf},%
+                labelsep=period,%
+                justification=raggedright,%
+                singlelinecheck=false,%
+                tableposition=top,font=small]
+                {caption}
+
+% \captionsetup*[table]{skip=\medskipamount}
+
+
+\RequirePackage{natbib}
+\renewcommand{\bibfont}{\small}
+% modifed from https://github.com/gbhutani/vancouver_authoryear_bibstyle/
+\IfFileExists{vancouver-elife-doi-fix.bst}
+  {\bibliographystyle{vancouver-elife-doi-fix}}
+  {\PackageWarning{elife}{vancouver-elife-doi-fix.bst not found; falling back to apalike bibliography style.}\bibliographystyle{apalike}}
+% Make author in citation italic
+\renewcommand{\NAT@nmfmt}[1]{{\bfseries\itshape\color{eLifeMediumGrey} #1}}
+
+% ...as well as the year
+\xpatchcmd{\NAT@citex}
+{\@citea\NAT@hyper@{\NAT@nmfmt{\NAT@nm}\NAT@date}}
+{\@citea\NAT@hyper@{\NAT@nmfmt{\NAT@nm}\NAT@nmfmt{\NAT@date}}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{\else\unskip\NAT@spacechar\NAT@hyper@{\NAT@date}}
+{\else\unskip\NAT@spacechar\NAT@hyper@{\NAT@nmfmt{\NAT@date}}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{\hyper@natlinkbreak{\NAT@aysep\NAT@spacechar}{\@citeb\@extra@b@citeb}\NAT@date}
+{\hyper@natlinkbreak{\NAT@nmfmt{\NAT@aysep\NAT@spacechar}}{\@citeb\@extra@b@citeb}\NAT@nmfmt{\NAT@date}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{\@citea\NAT@hyper@{\NAT@date}}
+{\@citea\NAT@hyper@{\NAT@nmfmt{\NAT@date}}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{{\@citeb\@extra@b@citeb}\NAT@date}
+{{\@citeb\@extra@b@citeb}\NAT@nmfmt{\NAT@date}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+%% There, we're finally done with patching the year in citations.
+
+%
+% headers and footers
+%
+\RequirePackage{fancyhdr}  % custom headers/footers
+\RequirePackage{lastpage}  % Number of pages in the document
+\pagestyle{fancy}          % Enables the custom headers/footers
+\addtolength{\headwidth}{\marginparsep}
+\addtolength{\headwidth}{\marginparwidth}
+\fancyhf{}
+% Removing header in v1.9
+% \chead{%
+% \setlength{\fboxsep}{3pt}
+% \colorbox{eLifeMediumGrey}{\begin{minipage}{\headwidth}\centering\color{white} Manuscript submitted to eLife\end{minipage}}%
+% }
+
+% Footers
+\rfoot{\small\color{eLifeMediumGrey}\thepage\space of\space\pageref{LastPage}}%
+\preto{\footrule}{\color{eLifeMediumGrey}}
+\renewcommand{\headrulewidth}{0pt}% % No header rule
+\renewcommand{\footrulewidth}{0.4pt}% % No footer rule
+
+%
+% section/subsection/paragraph set-up
+%
+\setcounter{secnumdepth}{0}
+\RequirePackage[explicit]{titlesec}
+\titleformat{\section}
+  {\color{eLifeMediumGrey}\Large\bfseries}
+  {\thesection}{}{#1}[]
+\titleformat{\subsection}
+  {\large\bfseries}
+  {\thesubsection}{}{#1}[]
+\titleformat{\subsubsection}
+  {\large}
+  {\thesubsubsection}{}{#1}[]    
+\titleformat{\paragraph}
+  {\color{eLifeMediumGrey}\large}
+  {\theparagraph}{}{#1}[] 
+\titlespacing*{\section}{0pc}{3ex \@plus4pt \@minus3pt}{0pt}
+\titlespacing*{\subsection}{0pc}{2.5ex \@plus3pt \@minus2pt}{0pt}
+\titlespacing*{\subsubsection}{0pc}{2ex \@plus2.5pt \@minus1.5pt}{0pt}
+\titlespacing*{\paragraph}{0pc}{1.5ex \@plus2pt \@minus1pt}{0pt}
+  
+\RequirePackage{enumitem}
+\setlist{noitemsep}
+
+\RequirePackage{alphalph}
+\newalphalph{\fnsymbolmult}[mult]{\@fnsymbol}{5}
+
+\newcounter{authorfn}
+\setcounter{authorfn}{1}
+\newcommand{\authfn}[1]{%
+  \fnsymbolmult{\numexpr\value{authorfn}+#1}%
+}
+
+\def\@correspondence{}
+\def\@contribution{}
+\def\@presentaddress{}
+\def\@deceased{}
+
+\newcommand{\corr}[2]{%
+  \ifx\empty\@correspondence\else\appto{\@correspondence}{; }{}{}\fi
+  \appto{\@correspondence}{%
+    \url{#1}%
+    \ifx\empty#2\else\space(#2)\fi
+  }{}{}%
+}
+
+\newcommand{\contrib}[2][]{
+  \appto{\@contribution}{%
+  \ifx\empty#1\else\textsuperscript{#1}\fi
+  #2\\
+  }{}{}
+}
+
+\newcommand{\presentadd}[2][]{
+  \ifx\empty\@presentaddress\else\appto{\@presentaddress}{; }{}{}\fi
+  \appto{\@presentaddress}{%
+  \ifx\empty#1\else\textsuperscript{#1}\fi
+  #2%
+  }{}{}
+}
+
+\newcommand{\deceased}[1]{\def\@deceased{\textsuperscript{#1}Deceased}}
+
+\reversemarginpar
+
+%
+% custom title page 
+%
+\renewcommand{\Authfont}{\bfseries\large\raggedright}
+\renewcommand{\Affilfont}{\mdseries\large\raggedright}
+\renewcommand{\Authands}{, }
+\setlength{\affilsep}{16pt}
+\renewcommand{\AB@affilsepx}{; \protect\Affilfont}
+
+\newcommand{\themetadata}{%
+    \textbf{*For correspondence:\\}  \@correspondence\par
+    \ifx\empty\@contribution\else
+    \bigskip\@contribution\par\fi
+    \ifx\empty\@presentaddress\else
+    \bigskip\textbf{Present address: }\@presentaddress\par\fi
+    \bigskip
+    \ifx\empty\@deceased\else\@deceased\par\fi
+}
+
+\patchcmd{\@author}{\AB@authlist\\[\affilsep]\AB@affillist}{\AB@authlist\\[\affilsep] 
+  \marginpar{\raggedright\footnotesize\themetadata\par}\AB@affillist}{}{}
+
+\renewcommand{\maketitle}{%
+  \vskip36pt%
+  {\color{eLifeDarkBlue}\raggedright\bfseries\fontsize{22}{27}\selectfont \@title\par}%
+  \vskip16pt
+  {\@author\par}
+  \vskip8pt
+}
+
+\renewenvironment{abstract}{%
+   \setlength{\parindent}{0pt}\raggedright
+   \textcolor{eLifeMediumGrey}{\rule{\textwidth}{2pt}}
+   \vskip16pt
+   \textcolor{eLifeLightBlue}{\large\bfseries\abstractname\space}
+}{%   
+   \vskip8pt
+   \textcolor{eLifeMediumGrey}{\rule{\textwidth}{2pt}}
+   \vskip16pt
+}
+
+%% Insert a grey line to separate floats from main text
+\newcommand{\topfigrule}{\vskip8pt\noindent{\rule{\linewidth}{1pt}}}
+\newcommand{\botfigrule}{\noindent{\rule{\linewidth}{1pt}}\vskip8pt}
+
+\RequirePackage{newfloat}
+\RequirePackage{wrapfig}
+\AtEndEnvironment{wrapfigure}{\vskip8pt\noindent{\rule{\hsize}{1pt}}}
+% \RequirePackage[lflt]{floatflt}
+% \AtEndEnvironment{floatingfigure}{\vskip8pt\noindent\textcolor{eLifeMediumGrey}{\rule{\hsize}{2pt}}}
+
+\DeclareFloatingEnvironment[placement=btp,name=Box]{featurebox}
+\captionsetup[featurebox]{font={Large,bf,color=eLifeDarkBlue}}
+
+% v1.11 2022-06 Updated many caption casing and dashes
+\newcounter{featurefigure}
+\newcounter{featuretable}
+\AtBeginEnvironment{featurebox}{%
+  \setcounter{featurefigure}{0}%
+  \setcounter{featuretable}{0}%
+  \newcommand{\featurefig}[1]{%
+    \refstepcounter{featurefigure}%
+    \vskip\smallskipamount%
+    {\small\textbf{\color{eLifeDarkBlue}Box \arabic{featurebox}---figure \arabic{featurefigure}.}\space #1\par}\medskip}
+  \newcommand{\featuretable}[1]{%
+    \refstepcounter{featuretable}%
+    \vskip\smallskipamount%
+    {\small\textbf{\color{eLifeDarkBlue}Box \arabic{featurebox}---table \arabic{featuretable}.}\space #1\par}\medskip}
+
+}
+\apptocmd{\featurebox}{%
+  \begin{mdframed}[linewidth=0pt,backgroundcolor=eLifeLightBlue!10,fontcolor=eLifeDarkBlue]
+  \if@reqslineno\addtolength{\linenumbersep}{1em}\internallinenumbers\fi%
+}{}{}
+\pretocmd{\endfeaturebox}{\end{mdframed}}{}{}
+
+
+\newenvironment{fullwidth}{%
+  \begin{adjustwidth}{-4.5cm}{}%
+  \hsize=\linewidth%
+}{\end{adjustwidth}}
+
+\appto{\appendix}{%
+  \captionsetup*[figure]{name={Appendix \arabic{appendix}---figure },font={color=eLifeDarkBlue,small},skip=\smallskipamount}%
+  \captionsetup*[table]{name={Appendix \arabic{appendix}---table },font={color=eLifeDarkBlue,small}}%
+}
+
+\newcounter{figsupp}
+\setcounter{figsupp}{0}
+\newcounter{data}
+\setcounter{data}{0}
+%% Added videos 2021/03/07
+\newcounter{srccode}
+\setcounter{srccode}{0}
+%% Added fig supp data and source code 2022/06
+\newcounter{fsdata}
+\setcounter{fsdata}{0}
+\newcounter{fssrccode}
+\setcounter{fssrccode}{0}
+%% Added videos 2018/06/03
+\newcounter{video}
+\setcounter{video}{0}
+\newcounter{videosupp}
+\setcounter{videosupp}{0}
+\def\supplist{}
+
+\RequirePackage{newfile}
+\newoutputstream{suppinfo}
+\openoutputfile{\jobname.suppinfo}{suppinfo}
+\addtostream{suppinfo}{\protect\setcounter{figure}{0}}
+
+% Added video source data and code 2022/06
+\DeclareRobustCommand{\video}[1]{%
+  \refstepcounter{video}%
+  \setcounter{data}{0}%
+  \setcounter{srccode}{0}%
+  \bigskip%
+  \noindent{\small\textbf{Video \arabic{video}.} #1\par}%
+  \bigskip
+}
+\DeclareRobustCommand{\videodata}[1]{%
+  \refstepcounter{data}%
+  \par\noindent{\small\textbf{Video~\thevideo---source data \arabic{data}.} #1}\par
+}
+\DeclareRobustCommand{\videosrccode}[1]{%
+  \refstepcounter{srccode}%
+  \par\noindent{\small\textbf{Video~\thevideo---source code \arabic{srccode}.} #1}\par
+}
+
+% Added fig supp source data and code 2022/06
+\DeclareRobustCommand{\figsuppsrccode}[1]{%
+  \protect\refstepcounter{fssrccode}%
+  \par\small\textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}---source code~\arabic{fssrccode}. } #1\par
+}
+\DeclareRobustCommand{\figsuppdata}[1]{%
+  \protect\refstepcounter{fsdata}%
+  \par\small\textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}---source data~\arabic{fsdata}. } #1\par
+}
+
+
+\AtBeginEnvironment{figure}{%
+  \setcounter{figsupp}{0}
+  \setcounter{data}{0}
+  \setcounter{videosupp}{0}
+  \setcounter{srccode}{0}
+  \addtostream{suppinfo}{
+    \protect\setcounter{figsupp}{0}
+    \protect\refstepcounter{figure}
+  }
+}
+
+\AtBeginEnvironment{wrapfigure}{%
+  \setcounter{figsupp}{0}
+  \setcounter{data}{0}
+  \setcounter{videosupp}{0}
+  \setcounter{srccode}{0}
+  \addtostream{suppinfo}{
+    \protect\setcounter{figsupp}{0}
+    \protect\refstepcounter{figure}
+  }
+}
+
+%% Updated 2017/06/30 to allow optional argument
+\DeclareRobustCommand{\figsupp}[3][]{%
+  \refstepcounter{figsupp}%
+  \addtostream{suppinfo}{%
+  \protect\refstepcounter{figsupp}
+  \protect\setcounter{fsdata}{0}
+  \protect\setcounter{fssrccode}{0}
+  }%
+  {%
+  \ifstrequal{#1}{none}{}{%
+    \small\textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}.} 
+    \ifstrempty{#1}{%
+      \renewcommand\figsuppdata[1]{}%
+      \renewcommand\figsuppsrccode[1]{}%
+      #2}{%
+      \renewcommand\figsuppdata[1]{}%
+      \renewcommand\figsuppsrccode[1]{}%
+      #1}}}\raggedright\par
+  \addtostream{suppinfo}{%
+    \noindent\protect\begin{minipage}{\linewidth}
+    \protect #3\noexpand\par
+    \textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}.} #2\noexpand\par
+    \vskip8pt
+    \protect\end{minipage}
+    \vskip16pt
+  }
+}
+\DeclareRobustCommand{\figdata}[1]{%
+  \refstepcounter{data}
+  {\small\textbf{\figurename~\thefigure---source data \arabic{data}.} #1}\par
+}
+%% Added 2021/03/07  
+\DeclareRobustCommand{\figsrccode}[1]{%
+  \refstepcounter{srccode}
+  {\small\textbf{\figurename~\thefigure---source code \arabic{srccode}.} #1}\par
+}
+%% Added 2018/06/03
+\DeclareRobustCommand{\videosupp}[1]{%
+  \refstepcounter{videosupp}
+  {\small\textbf{\figurename~\thefigure---video \arabic{videosupp}.} #1}\par
+}
+
+% Added table source data and code 2022/06
+\AtBeginEnvironment{table}{%
+  \setcounter{data}{0}
+  \setcounter{srccode}{0}
+  \setcounter{videosupp}{0}
+}
+
+\AtBeginEnvironment{wraptable}{%
+  \setcounter{data}{0}
+  \setcounter{srccode}{0}
+  \setcounter{videosupp}{0}
+}
+
+\DeclareRobustCommand{\tabledata}[1]{%
+  \refstepcounter{data}
+  {\small\textbf{\tablename~\thetable---source data \arabic{data}.} #1}\par
+}
+\DeclareRobustCommand{\tablesrccode}[1]{%
+  \refstepcounter{srccode}
+  {\small\textbf{\tablename~\thetable---source code \arabic{srccode}.} #1}\par
+}
+
+
+\AtEndDocument{%
+  \closeoutputstream{suppinfo}
+%   \pagestyle{empty}
+  \renewcommand{\footrule}{}
+  \rfoot{}
+  \input{\jobname.suppinfo}
+}
+
+\newcounter{appendix}
+\setcounter{appendix}{0}
+\newenvironment{appendixbox}{%
+  \setcounter{figure}{0}
+  \setcounter{table}{0}
+  \refstepcounter{appendix}%
+  \clearpage%
+  \patchcmd{\ttlf@section}{eLifeMediumGrey}{eLifeDarkBlue}{}{}
+  \noindent{\bfseries\Large\color{eLifeMediumGrey}Appendix \arabic{appendix}\par}
+  \nolinenumbers%
+  \begin{mdframed}[hidealllines=true,backgroundcolor=eLifeLightBlue!10,fontcolor=eLifeDarkBlue,leftline=true,linecolor=eLifeLightBlue,linewidth=1em]
+  \if@reqslineno\addtolength{\linenumbersep}{2em}\internallinenumbers\fi
+}{%
+  \end{mdframed}
+}
+
+\RequirePackage{hyperref}
+\hypersetup{colorlinks=true,allcolors=black,citecolor=eLifeMediumGrey,linkcolor=eLifeMediumGrey,urlcolor=eLifeLightBlue,hypertexnames=false}
+\urlstyle{sf}
+
+% Other desired commands
+\renewcommand{\equationautorefname}{Eq.}
+%% Added autoref support for \figsupp, \figdata, \video, \videosupp, (2021-03-04) \figsrccode
+% Added support for figsupp, video source data and code 2022/06
+\newcommand{\figsuppautorefname}{figure Supplement}
+\newcommand{\dataautorefname}{source data}
+\newcommand{\videoautorefname}{Video}
+\newcommand{\videosuppautorefname}{video}
+\newcommand{\srccodeautorefname}{source code}
+\newcommand{\FIGSUPP}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{figsupp:#2}%
+}
+\newcommand{\FIGDATA}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{figdata:#2}%
+}
+\newcommand{\TABLEDATA}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{tab:#1}---}\autoref{tabdata:#2}%
+}
+\newcommand{\VIDEODATA}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{video:#1}---}\autoref{viddata:#2}%
+}
+
+\newcommand{\FIGSRCCODE}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{figsrccode:#2}%
+}
+\newcommand{\TABLESRCCODE}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{tab:#1}---}\autoref{tabsrccode:#2}%
+}
+\newcommand{\VIDEOSRCCODE}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{video:#1}---}\autoref{vidsrccode:#2}%
+}
+
+\newcommand{\VIDEOSUPP}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{videosupp:#2}%
+}
+\newcommand{\FIG}[1]{\autoref{fig:#1}}
+\newcommand{\TABLE}[1]{\autoref{tab:#1}}
+\newcommand{\VIDEO}[1]{\autoref{video:#1}}
+\newcommand{\EQ}[1]{\autoref{eq:#1}}
+\newcommand{\BOX}[1]{\autoref{box:#1}}
+\let\oldautoref\autoref
+\renewcommand{\autoref}[1]{\emph{\textbf{\oldautoref{#1}}}}
+
+\endinput
diff --git a/texmf/tex/latex/elife/elife.cls b/texmf/tex/latex/elife/elife.cls
new file mode 100755
index 0000000..3d2c299
--- /dev/null
+++ b/texmf/tex/latex/elife/elife.cls
@@ -0,0 +1,527 @@
+% A template for eLife submissions.
+%
+% Created by Overleaf (writeLaTeX).
+%
+\NeedsTeXFormat{LaTeX2e}
+\ProvidesClass{elife}[2022/06/01, v1.11]
+
+%% Move all option processing before loading class
+\newif\if@reqslineno
+\DeclareOption{lineno}{\@reqslinenotrue}
+
+%% Linespacing.
+\newif\if@onehalfspacing
+\newif\if@doublespacing
+\DeclareOption{onehalfspacing}{\@onehalfspacingtrue}
+\DeclareOption{doublespacing}{\@doublespacingtrue}
+
+\DeclareOption*{\PassOptionsToClass{\CurrentOption}{extarticle}}
+\ExecuteOptions{}
+\ProcessOptions\relax
+\LoadClass{extarticle}
+
+\RequirePackage[english]{babel}
+
+\RequirePackage{calc}
+\RequirePackage{etoolbox}
+\RequirePackage{regexpatch}
+\RequirePackage{ifxetex,ifluatex}
+
+\newif\ifxetexorluatex
+\ifxetex
+  \xetexorluatextrue
+\else
+  \ifluatex
+    \xetexorluatextrue
+  \else
+    \xetexorluatexfalse
+  \fi
+\fi
+
+\RequirePackage{amsmath}
+\RequirePackage{mdframed}
+
+\RequirePackage{lineno}
+\if@reqslineno\linenumbers\fi
+
+% Note v1.0 of elife.cls used Trueno font; this was 
+% changed to use Open Sans in v1.1
+\ifxetexorluatex
+  \RequirePackage{unicode-math}
+  % v1.7: xits-math font name changed to XITSMath in TL2019
+  \RequirePackage[default]{opensans}
+  \setmonofont[Scale=MatchUppercase]{Latin Modern Mono}
+  % XITSMath is really STIX. Really.
+  % https://tex.stackexchange.com/questions/227216/stix-versus-xits
+  \setmathfont[Extension = .otf,BoldFont = XITSMath-Bold,]{XITSMath-Regular}
+\else  
+  \RequirePackage[T1]{fontenc}
+  \RequirePackage[utf8]{inputenc}
+  \RequirePackage{stix}
+  \RequirePackage[default]{opensans}
+  \renewcommand{\ttdefault}{lmtt}
+\fi
+
+\RequirePackage{microtype}
+
+% Trueno/Open Sans requires a bigger "single" linespread.
+\linespread{1.2}
+\if@onehalfspacing\linespread{1.5}\fi
+\if@doublespacing\linespread{2.0}\fi
+
+\RequirePackage{graphicx,xcolor}
+\definecolor{eLifeDarkBlue}{HTML}{273B81}
+\definecolor{eLifeLightBlue}{HTML}{0A9DD9}
+\definecolor{eLifeMediumGrey}{HTML}{6D6E70}
+\definecolor{eLifeLightGrey}{HTML}{929497}
+
+\RequirePackage{booktabs}
+\RequirePackage{authblk}
+
+\RequirePackage[left=6cm,%
+                marginparwidth=4cm,%
+                marginparsep=0.5cm,%
+                right=1.3cm,%
+                top=2cm,%
+                bottom=2.5cm,%
+                headheight=21pt,%
+                headsep=2\baselineskip,%
+                columnsep=2em,%
+                letterpaper]{geometry}%
+\RequirePackage{changepage}
+
+\RequirePackage{silence}
+\WarningFilter{caption}{The option `hypcap=true' will be ignored}
+
+\RequirePackage[labelfont={bf},%
+                labelsep=period,%
+                justification=raggedright,%
+                singlelinecheck=false,%
+                tableposition=top,font=small]
+                {caption}
+
+% \captionsetup*[table]{skip=\medskipamount}
+
+
+\RequirePackage{natbib}
+\renewcommand{\bibfont}{\small}
+% modifed from https://github.com/gbhutani/vancouver_authoryear_bibstyle/
+\IfFileExists{vancouver-elife.bst}
+  {\bibliographystyle{vancouver-elife}}
+  {\PackageWarning{elife}{vancouver-elife.bst not found; falling back to apalike bibliography style.}\bibliographystyle{apalike}}
+% Make author in citation italic
+\renewcommand{\NAT@nmfmt}[1]{{\bfseries\itshape\color{eLifeMediumGrey} #1}}
+
+% ...as well as the year
+\xpatchcmd{\NAT@citex}
+{\@citea\NAT@hyper@{\NAT@nmfmt{\NAT@nm}\NAT@date}}
+{\@citea\NAT@hyper@{\NAT@nmfmt{\NAT@nm}\NAT@nmfmt{\NAT@date}}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{\else\unskip\NAT@spacechar\NAT@hyper@{\NAT@date}}
+{\else\unskip\NAT@spacechar\NAT@hyper@{\NAT@nmfmt{\NAT@date}}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{\hyper@natlinkbreak{\NAT@aysep\NAT@spacechar}{\@citeb\@extra@b@citeb}\NAT@date}
+{\hyper@natlinkbreak{\NAT@nmfmt{\NAT@aysep\NAT@spacechar}}{\@citeb\@extra@b@citeb}\NAT@nmfmt{\NAT@date}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{\@citea\NAT@hyper@{\NAT@date}}
+{\@citea\NAT@hyper@{\NAT@nmfmt{\NAT@date}}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+
+\xpatchcmd{\NAT@citex}
+{{\@citeb\@extra@b@citeb}\NAT@date}
+{{\@citeb\@extra@b@citeb}\NAT@nmfmt{\NAT@date}}
+{}{\PackageWarning{eLife}{Failed to patch year format in citation}}
+%% There, we're finally done with patching the year in citations.
+
+%
+% headers and footers
+%
+\RequirePackage{fancyhdr}  % custom headers/footers
+\RequirePackage{lastpage}  % Number of pages in the document
+\pagestyle{fancy}          % Enables the custom headers/footers
+\addtolength{\headwidth}{\marginparsep}
+\addtolength{\headwidth}{\marginparwidth}
+\fancyhf{}
+% Removing header in v1.9
+% \chead{%
+% \setlength{\fboxsep}{3pt}
+% \colorbox{eLifeMediumGrey}{\begin{minipage}{\headwidth}\centering\color{white} Manuscript submitted to eLife\end{minipage}}%
+% }
+
+% Footers
+\rfoot{\small\color{eLifeMediumGrey}\thepage\space of\space\pageref{LastPage}}%
+\preto{\footrule}{\color{eLifeMediumGrey}}
+\renewcommand{\headrulewidth}{0pt}% % No header rule
+\renewcommand{\footrulewidth}{0.4pt}% % No footer rule
+
+%
+% section/subsection/paragraph set-up
+%
+\setcounter{secnumdepth}{0}
+\RequirePackage[explicit]{titlesec}
+\titleformat{\section}
+  {\color{eLifeMediumGrey}\Large\bfseries}
+  {\thesection}{}{#1}[]
+\titleformat{\subsection}
+  {\large\bfseries}
+  {\thesubsection}{}{#1}[]
+\titleformat{\subsubsection}
+  {\large}
+  {\thesubsubsection}{}{#1}[]    
+\titleformat{\paragraph}
+  {\color{eLifeMediumGrey}\large}
+  {\theparagraph}{}{#1}[] 
+\titlespacing*{\section}{0pc}{3ex \@plus4pt \@minus3pt}{0pt}
+\titlespacing*{\subsection}{0pc}{2.5ex \@plus3pt \@minus2pt}{0pt}
+\titlespacing*{\subsubsection}{0pc}{2ex \@plus2.5pt \@minus1.5pt}{0pt}
+\titlespacing*{\paragraph}{0pc}{1.5ex \@plus2pt \@minus1pt}{0pt}
+  
+\RequirePackage{enumitem}
+\setlist{noitemsep}
+
+\RequirePackage{alphalph}
+\newalphalph{\fnsymbolmult}[mult]{\@fnsymbol}{5}
+
+\newcounter{authorfn}
+\setcounter{authorfn}{1}
+\newcommand{\authfn}[1]{%
+  \fnsymbolmult{\numexpr\value{authorfn}+#1}%
+}
+
+\def\@correspondence{}
+\def\@contribution{}
+\def\@presentaddress{}
+\def\@deceased{}
+
+\newcommand{\corr}[2]{%
+  \ifx\empty\@correspondence\else\appto{\@correspondence}{; }{}{}\fi
+  \appto{\@correspondence}{%
+    \url{#1}%
+    \ifx\empty#2\else\space(#2)\fi
+  }{}{}%
+}
+
+\newcommand{\contrib}[2][]{
+  \appto{\@contribution}{%
+  \ifx\empty#1\else\textsuperscript{#1}\fi
+  #2\\
+  }{}{}
+}
+
+\newcommand{\presentadd}[2][]{
+  \ifx\empty\@presentaddress\else\appto{\@presentaddress}{; }{}{}\fi
+  \appto{\@presentaddress}{%
+  \ifx\empty#1\else\textsuperscript{#1}\fi
+  #2%
+  }{}{}
+}
+
+\newcommand{\deceased}[1]{\def\@deceased{\textsuperscript{#1}Deceased}}
+
+\reversemarginpar
+
+%
+% custom title page 
+%
+\renewcommand{\Authfont}{\bfseries\large\raggedright}
+\renewcommand{\Affilfont}{\mdseries\large\raggedright}
+\renewcommand{\Authands}{, }
+\setlength{\affilsep}{16pt}
+\renewcommand{\AB@affilsepx}{; \protect\Affilfont}
+
+\newcommand{\themetadata}{%
+    \textbf{*For correspondence:\\}  \@correspondence\par
+    \ifx\empty\@contribution\else
+    \bigskip\@contribution\par\fi
+    \ifx\empty\@presentaddress\else
+    \bigskip\textbf{Present address: }\@presentaddress\par\fi
+    \bigskip
+    \ifx\empty\@deceased\else\@deceased\par\fi
+}
+
+\patchcmd{\@author}{\AB@authlist\\[\affilsep]\AB@affillist}{\AB@authlist\\[\affilsep] 
+  \marginpar{\raggedright\footnotesize\themetadata\par}\AB@affillist}{}{}
+
+\renewcommand{\maketitle}{%
+  \vskip36pt%
+  {\color{eLifeDarkBlue}\raggedright\bfseries\fontsize{22}{27}\selectfont \@title\par}%
+  \vskip16pt
+  {\@author\par}
+  \vskip8pt
+}
+
+\renewenvironment{abstract}{%
+   \setlength{\parindent}{0pt}\raggedright
+   \textcolor{eLifeMediumGrey}{\rule{\textwidth}{2pt}}
+   \vskip16pt
+   \textcolor{eLifeLightBlue}{\large\bfseries\abstractname\space}
+}{%   
+   \vskip8pt
+   \textcolor{eLifeMediumGrey}{\rule{\textwidth}{2pt}}
+   \vskip16pt
+}
+
+%% Insert a grey line to separate floats from main text
+\newcommand{\topfigrule}{\vskip8pt\noindent{\rule{\linewidth}{1pt}}}
+\newcommand{\botfigrule}{\noindent{\rule{\linewidth}{1pt}}\vskip8pt}
+
+\RequirePackage{newfloat}
+\RequirePackage{wrapfig}
+\AtEndEnvironment{wrapfigure}{\vskip8pt\noindent{\rule{\hsize}{1pt}}}
+% \RequirePackage[lflt]{floatflt}
+% \AtEndEnvironment{floatingfigure}{\vskip8pt\noindent\textcolor{eLifeMediumGrey}{\rule{\hsize}{2pt}}}
+
+\DeclareFloatingEnvironment[placement=btp,name=Box]{featurebox}
+\captionsetup[featurebox]{font={Large,bf,color=eLifeDarkBlue}}
+
+% v1.11 2022-06 Updated many caption casing and dashes
+\newcounter{featurefigure}
+\newcounter{featuretable}
+\AtBeginEnvironment{featurebox}{%
+  \setcounter{featurefigure}{0}%
+  \setcounter{featuretable}{0}%
+  \newcommand{\featurefig}[1]{%
+    \refstepcounter{featurefigure}%
+    \vskip\smallskipamount%
+    {\small\textbf{\color{eLifeDarkBlue}Box \arabic{featurebox}---figure \arabic{featurefigure}.}\space #1\par}\medskip}
+  \newcommand{\featuretable}[1]{%
+    \refstepcounter{featuretable}%
+    \vskip\smallskipamount%
+    {\small\textbf{\color{eLifeDarkBlue}Box \arabic{featurebox}---table \arabic{featuretable}.}\space #1\par}\medskip}
+
+}
+\apptocmd{\featurebox}{%
+  \begin{mdframed}[linewidth=0pt,backgroundcolor=eLifeLightBlue!10,fontcolor=eLifeDarkBlue]
+  \if@reqslineno\addtolength{\linenumbersep}{1em}\internallinenumbers\fi%
+}{}{}
+\pretocmd{\endfeaturebox}{\end{mdframed}}{}{}
+
+
+\newenvironment{fullwidth}{%
+  \begin{adjustwidth}{-4.5cm}{}%
+  \hsize=\linewidth%
+}{\end{adjustwidth}}
+
+\appto{\appendix}{%
+  \captionsetup*[figure]{name={Appendix \arabic{appendix}---figure },font={color=eLifeDarkBlue,small},skip=\smallskipamount}%
+  \captionsetup*[table]{name={Appendix \arabic{appendix}---table },font={color=eLifeDarkBlue,small}}%
+}
+
+\newcounter{figsupp}
+\setcounter{figsupp}{0}
+\newcounter{data}
+\setcounter{data}{0}
+%% Added videos 2021/03/07
+\newcounter{srccode}
+\setcounter{srccode}{0}
+%% Added fig supp data and source code 2022/06
+\newcounter{fsdata}
+\setcounter{fsdata}{0}
+\newcounter{fssrccode}
+\setcounter{fssrccode}{0}
+%% Added videos 2018/06/03
+\newcounter{video}
+\setcounter{video}{0}
+\newcounter{videosupp}
+\setcounter{videosupp}{0}
+\def\supplist{}
+
+\RequirePackage{newfile}
+\newoutputstream{suppinfo}
+\openoutputfile{\jobname.suppinfo}{suppinfo}
+\addtostream{suppinfo}{\protect\setcounter{figure}{0}}
+
+% Added video source data and code 2022/06
+\DeclareRobustCommand{\video}[1]{%
+  \refstepcounter{video}%
+  \setcounter{data}{0}%
+  \setcounter{srccode}{0}%
+  \bigskip%
+  \noindent{\small\textbf{Video \arabic{video}.} #1\par}%
+  \bigskip
+}
+\DeclareRobustCommand{\videodata}[1]{%
+  \refstepcounter{data}%
+  \par\noindent{\small\textbf{Video~\thevideo---source data \arabic{data}.} #1}\par
+}
+\DeclareRobustCommand{\videosrccode}[1]{%
+  \refstepcounter{srccode}%
+  \par\noindent{\small\textbf{Video~\thevideo---source code \arabic{srccode}.} #1}\par
+}
+
+% Added fig supp source data and code 2022/06
+\DeclareRobustCommand{\figsuppsrccode}[1]{%
+  \protect\refstepcounter{fssrccode}%
+  \par\small\textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}---source code~\arabic{fssrccode}. } #1\par
+}
+\DeclareRobustCommand{\figsuppdata}[1]{%
+  \protect\refstepcounter{fsdata}%
+  \par\small\textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}---source data~\arabic{fsdata}. } #1\par
+}
+
+
+\AtBeginEnvironment{figure}{%
+  \setcounter{figsupp}{0}
+  \setcounter{data}{0}
+  \setcounter{videosupp}{0}
+  \setcounter{srccode}{0}
+  \addtostream{suppinfo}{
+    \protect\setcounter{figsupp}{0}
+    \protect\refstepcounter{figure}
+  }
+}
+
+\AtBeginEnvironment{wrapfigure}{%
+  \setcounter{figsupp}{0}
+  \setcounter{data}{0}
+  \setcounter{videosupp}{0}
+  \setcounter{srccode}{0}
+  \addtostream{suppinfo}{
+    \protect\setcounter{figsupp}{0}
+    \protect\refstepcounter{figure}
+  }
+}
+
+%% Updated 2017/06/30 to allow optional argument
+\DeclareRobustCommand{\figsupp}[3][]{%
+  \refstepcounter{figsupp}%
+  \addtostream{suppinfo}{%
+  \protect\refstepcounter{figsupp}
+  \protect\setcounter{fsdata}{0}
+  \protect\setcounter{fssrccode}{0}
+  }%
+  {%
+  \ifstrequal{#1}{none}{}{%
+    \small\textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}.} 
+    \ifstrempty{#1}{%
+      \renewcommand\figsuppdata[1]{}%
+      \renewcommand\figsuppsrccode[1]{}%
+      #2}{%
+      \renewcommand\figsuppdata[1]{}%
+      \renewcommand\figsuppsrccode[1]{}%
+      #1}}}\raggedright\par
+  \addtostream{suppinfo}{%
+    \noindent\protect\begin{minipage}{\linewidth}
+    \protect #3\noexpand\par
+    \textbf{\figurename~\thefigure---figure supplement \arabic{figsupp}.} #2\noexpand\par
+    \vskip8pt
+    \protect\end{minipage}
+    \vskip16pt
+  }
+}
+\DeclareRobustCommand{\figdata}[1]{%
+  \refstepcounter{data}
+  {\small\textbf{\figurename~\thefigure---source data \arabic{data}.} #1}\par
+}
+%% Added 2021/03/07  
+\DeclareRobustCommand{\figsrccode}[1]{%
+  \refstepcounter{srccode}
+  {\small\textbf{\figurename~\thefigure---source code \arabic{srccode}.} #1}\par
+}
+%% Added 2018/06/03
+\DeclareRobustCommand{\videosupp}[1]{%
+  \refstepcounter{videosupp}
+  {\small\textbf{\figurename~\thefigure---video \arabic{videosupp}.} #1}\par
+}
+
+% Added table source data and code 2022/06
+\AtBeginEnvironment{table}{%
+  \setcounter{data}{0}
+  \setcounter{srccode}{0}
+  \setcounter{videosupp}{0}
+}
+
+\AtBeginEnvironment{wraptable}{%
+  \setcounter{data}{0}
+  \setcounter{srccode}{0}
+  \setcounter{videosupp}{0}
+}
+
+\DeclareRobustCommand{\tabledata}[1]{%
+  \refstepcounter{data}
+  {\small\textbf{\tablename~\thetable---source data \arabic{data}.} #1}\par
+}
+\DeclareRobustCommand{\tablesrccode}[1]{%
+  \refstepcounter{srccode}
+  {\small\textbf{\tablename~\thetable---source code \arabic{srccode}.} #1}\par
+}
+
+
+\AtEndDocument{%
+  \closeoutputstream{suppinfo}
+%   \pagestyle{empty}
+  \renewcommand{\footrule}{}
+  \rfoot{}
+  \input{\jobname.suppinfo}
+}
+
+\newcounter{appendix}
+\setcounter{appendix}{0}
+\newenvironment{appendixbox}{%
+  \setcounter{figure}{0}
+  \setcounter{table}{0}
+  \refstepcounter{appendix}%
+  \clearpage%
+  \patchcmd{\ttlf@section}{eLifeMediumGrey}{eLifeDarkBlue}{}{}
+  \noindent{\bfseries\Large\color{eLifeMediumGrey}Appendix \arabic{appendix}\par}
+  \nolinenumbers%
+  \begin{mdframed}[hidealllines=true,backgroundcolor=eLifeLightBlue!10,fontcolor=eLifeDarkBlue,leftline=true,linecolor=eLifeLightBlue,linewidth=1em]
+  \if@reqslineno\addtolength{\linenumbersep}{2em}\internallinenumbers\fi
+}{%
+  \end{mdframed}
+}
+
+\RequirePackage{hyperref}
+\hypersetup{colorlinks=true,allcolors=black,citecolor=eLifeMediumGrey,linkcolor=eLifeMediumGrey,urlcolor=eLifeLightBlue,hypertexnames=false}
+\urlstyle{sf}
+
+% Other desired commands
+\renewcommand{\equationautorefname}{Eq.}
+%% Added autoref support for \figsupp, \figdata, \video, \videosupp, (2021-03-04) \figsrccode
+% Added support for figsupp, video source data and code 2022/06
+\newcommand{\figsuppautorefname}{figure Supplement}
+\newcommand{\dataautorefname}{source data}
+\newcommand{\videoautorefname}{Video}
+\newcommand{\videosuppautorefname}{video}
+\newcommand{\srccodeautorefname}{source code}
+\newcommand{\FIGSUPP}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{figsupp:#2}%
+}
+\newcommand{\FIGDATA}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{figdata:#2}%
+}
+\newcommand{\TABLEDATA}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{tab:#1}---}\autoref{tabdata:#2}%
+}
+\newcommand{\VIDEODATA}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{video:#1}---}\autoref{viddata:#2}%
+}
+
+\newcommand{\FIGSRCCODE}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{figsrccode:#2}%
+}
+\newcommand{\TABLESRCCODE}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{tab:#1}---}\autoref{tabsrccode:#2}%
+}
+\newcommand{\VIDEOSRCCODE}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{video:#1}---}\autoref{vidsrccode:#2}%
+}
+
+\newcommand{\VIDEOSUPP}[2][]{%
+  \ifstrequal{#1}{}{}{\autoref{fig:#1}---}\autoref{videosupp:#2}%
+}
+\newcommand{\FIG}[1]{\autoref{fig:#1}}
+\newcommand{\TABLE}[1]{\autoref{tab:#1}}
+\newcommand{\VIDEO}[1]{\autoref{video:#1}}
+\newcommand{\EQ}[1]{\autoref{eq:#1}}
+\newcommand{\BOX}[1]{\autoref{box:#1}}
+\let\oldautoref\autoref
+\renewcommand{\autoref}[1]{\emph{\textbf{\oldautoref{#1}}}}
+
+\endinput
\ No newline at end of file